Expression, regulation and putative nutrient-sensing function of taste GPCRs in the heart.

G protein-coupled receptors (GPCRs) are critical for cardiovascular physiology. Cardiac cells express >100 nonchemosensory GPCRs, indicating that important physiological and potential therapeutic targets remain to be discovered. Moreover, there is a growing appreciation that members of the large,...

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Bibliographic Details
Main Authors: Simon R Foster, Enzo R Porrello, Brooke Purdue, Hsiu-Wen Chan, Anja Voigt, Sabine Frenzel, Ross D Hannan, Karen M Moritz, David G Simmons, Peter Molenaar, Eugeni Roura, Ulrich Boehm, Wolfgang Meyerhof, Walter G Thomas
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3655793?pdf=render