Hypoxia Modulates the Response of Mast Cells to Staphylococcus aureus Infection

To study the antimicrobial function of immune cells ex vivo, cells are commonly cultivated under atmospheric oxygen concentrations (20–21%; normoxia), although the physiological oxygen conditions in vivo are significantly lower in most tissues. Especially during an acute infection, oxygen concentrat...

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Bibliographic Details
Main Authors: Helene Möllerherm, Katja Branitzki-Heinemann, Graham Brogden, Ayssar A. Elamin, Wulf Oehlmann, Herbert Fuhrmann, Mahavir Singh, Hassan Y. Naim, Maren von Köckritz-Blickwede
Format: Article
Language:English
Published: Frontiers Media S.A. 2017-05-01
Series:Frontiers in Immunology
Subjects:
Online Access:http://journal.frontiersin.org/article/10.3389/fimmu.2017.00541/full