Modulation of the pentose phosphate pathway induces endodermal differentiation in embryonic stem cells.

Modulation of the pentose phosphate pathway induces endodermal differentiation in embryonic stem cells.

Embryonic stem (ES) cells can differentiate in vitro into a variety of cell types. Efforts to produce endodermal cell derivatives, including lung, liver and pancreas, have been met with modest success. Understanding how the endoderm originates from ES cells is the first step to generate specific cel...

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Bibliographic Details
Main Authors: Genesia Manganelli, Annalisa Fico, Ugo Masullo, Fabiana Pizzolongo, Amelia Cimmino, Stefania Filosa
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3257253?pdf=render

Internet

http://europepmc.org/articles/PMC3257253?pdf=render

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