Multiplexed live-cell profiling with Raman probes

Currently relatively few functional probes for Raman-based live-cell profiling exist. Here the authors build on their previous ultra-bright Raman dots to devise a 14-plexed Raman probe panel to quantify cell surface proteins, endocytosis activities and metabolic dynamics of single live cells.

Bibliographic Details
Main Authors: Chen Chen, Zhilun Zhao, Naixin Qian, Shixuan Wei, Fanghao Hu, Wei Min
Format: Article
Language:English
Published: Nature Publishing Group 2021-06-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-021-23700-0