Modulation of Mucosal Immune Response, Tolerance and Proliferation in Mice Colonized by the Mucin-Degrader Akkermansia muciniphila

Epithelial cells of the mammalian intestine are covered with a mucus layer that prevents direct contact with intestinal microbes but also constitutes a substrate for mucus-degrading bacteria. To study the effect of mucus degradation on the host-response, germ-free mice were colonized with Akkermansi...

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Bibliographic Details
Main Authors: Muriel eDerrien, Peter evan Baarlen, Guido eHooiveld, Elisabeth eNorin, Michael eMuller, Willem ede Vos
Format: Article
Language:English
Published: Frontiers Media S.A. 2011-08-01
Series:Frontiers in Cellular and Infection Microbiology
Subjects:
Online Access:http://journal.frontiersin.org/Journal/10.3389/fmicb.2011.00166/full