Inhibition of PKC/MEK pathway suppresses β1-integrin and mitigates breast cancer cells proliferation

Inhibition of PKC/MEK pathway suppresses β1-integrin and mitigates breast cancer cells proliferation

Prostaglandin E2 (PGE2) and β1-integrin have been correlated with breast cancer, where both could enhance progression and metastasis. Protein kinase C (PKC) and MEK have played a vital role in breast cancer development. Our study was conducted to elucidate the effect of inhibition of E-prostanoid re...

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Bibliographic Details
Main Authors: Nahla E. EL-Ashmawy, Enas A. EL-Zamarany, Naglaa F. Khedr, Hend M. Selim, Eman G. Khedr
Format: Article
Language:English
Published: Elsevier 2021-01-01
Series:Toxicology Reports
Subjects:
Breast cancer
E2F1
FOXC2
NF-ҡB
Prostaglandin E2
β1-integrin
Online Access:http://www.sciencedirect.com/science/article/pii/S2214750021001396

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http://www.sciencedirect.com/science/article/pii/S2214750021001396

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