Single nucleotide polymorphisms within interferon signaling pathway genes are associated with colorectal cancer susceptibility and survival.

Single nucleotide polymorphisms within interferon signaling pathway genes are associated with colorectal cancer susceptibility and survival.

Interferon (IFN) signaling has been suggested to play an important role in colorectal carcinogenesis. Our study aimed to examine potentially functional genetic variants in interferon regulatory factor 3 (IRF3), IRF5, IRF7, type I and type II IFN and their receptor genes with respect to colorectal ca...

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Bibliographic Details
Main Authors: Shun Lu, Barbara Pardini, Bowang Cheng, Alessio Naccarati, Stefanie Huhn, Veronika Vymetalkova, Ludmila Vodickova, Thomas Buchler, Kari Hemminki, Pavel Vodicka, Asta Försti
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4211713?pdf=render

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http://europepmc.org/articles/PMC4211713?pdf=render

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