Kv4.2 knockout mice display learning and memory deficits in the Lashley maze [version 2; referees: 2 approved]
Background: Potassium channels have been shown to be involved in neural plasticity and learning. Kv4.2 is a subunit of the A-type potassium channel. Kv4.2 channels modulate excitability in the dendrites of pyramidal neurons in the cortex and hippocampus. Deletion of Kv4.2 results in spatial learning...
Main Authors: | , , |
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Format: | Article |
Language: | English |
Published: |
F1000 Research Ltd
2017-02-01
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Series: | F1000Research |
Subjects: | |
Online Access: | https://f1000research.com/articles/5-2456/v2 |