Kv4.2 knockout mice display learning and memory deficits in the Lashley maze [version 2; referees: 2 approved]

Background: Potassium channels have been shown to be involved in neural plasticity and learning. Kv4.2 is a subunit of the A-type potassium channel. Kv4.2 channels modulate excitability in the dendrites of pyramidal neurons in the cortex and hippocampus. Deletion of Kv4.2 results in spatial learning...

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Bibliographic Details
Main Authors: Gregory D. Smith, Nan Gao, Joaquin N. Lugo
Format: Article
Language:English
Published: F1000 Research Ltd 2017-02-01
Series:F1000Research
Subjects:
Online Access:https://f1000research.com/articles/5-2456/v2