Inhibition of PTGS1 promotes osteogenic differentiation of adipose-derived stem cells by suppressing NF-kB signaling

Inhibition of PTGS1 promotes osteogenic differentiation of adipose-derived stem cells by suppressing NF-kB signaling

Abstract Background Tissue inflammation is an important problem in the field of human adipose-derived stem cell (ASC)-based therapeutic bone regeneration. Many studies indicate that inflammatory cytokines are disadvantageous for osteogenic differentiation and bone formation. Therefore, overcoming in...

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Bibliographic Details
Main Authors: Yuejun Wang, Yunsong Liu, Min Zhang, Longwei Lv, Xiao Zhang, Ping Zhang, Yongsheng Zhou
Format: Article
Language:English
Published: BMC 2019-02-01
Series:Stem Cell Research & Therapy
Subjects:
PTGS1
NF-κB
Osteogenic differentiation
ASCs
Online Access:http://link.springer.com/article/10.1186/s13287-019-1167-3

Internet

http://link.springer.com/article/10.1186/s13287-019-1167-3

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