Trans‐generational epigenetic regulation associated with the amelioration of Duchenne Muscular Dystrophy

Trans‐generational epigenetic regulation associated with the amelioration of Duchenne Muscular Dystrophy

Abstract Exon skipping is an effective strategy for the treatment of many Duchenne Muscular Dystrophy (DMD) mutations. Natural exon skipping observed in several DMD cases can help in identifying novel therapeutic tools. Here, we show a DMD study case where the lack of a splicing factor (Celf2a), whi...

Full description

Bibliographic Details
Main Authors: Julie Martone, Michela Lisi, Francesco Castagnetti, Alessandro Rosa, Valerio Di Carlo, Enrique Blanco, Adriano Setti, Davide Mariani, Alessio Colantoni, Tiziana Santini, Lucia Perone, Luciano Di Croce, Irene Bozzoni
Format: Article
Language:English
Published: Wiley 2020-08-01
Series:EMBO Molecular Medicine
Subjects:
ATAC sequencing
DMD Exon skipping
iPSC Reprogramming
lncRNAs
trans‐generational epigenetic inheritance
Online Access:https://doi.org/10.15252/emmm.202012063

Internet

https://doi.org/10.15252/emmm.202012063

Similar Items