Comparison of false-discovery rates of various decoy databases

Abstract Background The target-decoy strategy effectively estimates the false-discovery rate (FDR) by creating a decoy database with a size identical to that of the target database. Decoy databases are created by various methods, such as, the reverse, pseudo-reverse, shuffle, pseudo-shuffle, and the...

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Bibliographic Details
Main Authors: Sangjeong Lee, Heejin Park, Hyunwoo Kim
Format: Article
Language:English
Published: BMC 2021-09-01
Series:Proteome Science
Subjects:
Online Access:https://doi.org/10.1186/s12953-021-00179-7