Hydroxysafflor Yellow A Alleviates Ovalbumin-Induced Asthma in a Guinea Pig Model by Attenuateing the Expression of Inflammatory Cytokines and Signal Transduction

Hydroxysafflor Yellow A Alleviates Ovalbumin-Induced Asthma in a Guinea Pig Model by Attenuateing the Expression of Inflammatory Cytokines and Signal Transduction

Hydroxysafflor yellow A (HSYA) is an effective ingredient of the Chinese herb Carthamus tinctorius L. In this study, we aimed to evaluate the effects of HSYA on ovalbumin (OVA)-induced asthma in guinea pigs, and to elucidate the underlying mechanisms. We established a guinea pig asthma model by intr...

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Bibliographic Details
Main Authors: Meng Zheng, Xinjing Guo, Ruiyan Pan, Jianwei Gao, Baoxia Zang, Ming Jin
Format: Article
Language:English
Published: Frontiers Media S.A. 2019-04-01
Series:Frontiers in Pharmacology
Subjects:
Hydroxysafflor yellow A
asthma
Th1
Th2
MAPK pathway
inflammation
Online Access:https://www.frontiersin.org/article/10.3389/fphar.2019.00328/full

Internet

https://www.frontiersin.org/article/10.3389/fphar.2019.00328/full

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