Hydroxysafflor Yellow A Alleviates Ovalbumin-Induced Asthma in a Guinea Pig Model by Attenuateing the Expression of Inflammatory Cytokines and Signal Transduction
Hydroxysafflor yellow A (HSYA) is an effective ingredient of the Chinese herb Carthamus tinctorius L. In this study, we aimed to evaluate the effects of HSYA on ovalbumin (OVA)-induced asthma in guinea pigs, and to elucidate the underlying mechanisms. We established a guinea pig asthma model by intr...
Main Authors: | Meng Zheng, Xinjing Guo, Ruiyan Pan, Jianwei Gao, Baoxia Zang, Ming Jin |
---|---|
Format: | Article |
Language: | English |
Published: |
Frontiers Media S.A.
2019-04-01
|
Series: | Frontiers in Pharmacology |
Subjects: | |
Online Access: | https://www.frontiersin.org/article/10.3389/fphar.2019.00328/full |
Similar Items
-
Hydroxysafflor Yellow A Suppresses Platelet Activating Factor-Induced Activation of Human Small Airway Epithelial Cells
by: Xinjing Guo, et al.
Published: (2018-08-01) -
Hydroxysafflor Yellow A Suppresses MRC-5 Cell Activation Induced by TGF-β1 by Blocking TGF-β1 Binding to TβRII
by: Ruiyan Pan, et al.
Published: (2017-05-01) -
Hydroxysafflor yellow A (HSYA) alleviates apoptosis and autophagy of neural stem cells induced by heat stress via p38 MAPK/MK2/Hsp27-78 signaling pathway
by: Hongbo Li, et al.
Published: (2019-06-01) -
Hydroxysafflor yellow A suppresses angiogenesis of hepatocellular carcinoma through inhibition of p38 MAPK phosphorylation
by: Jingyu Zhang, et al.
Published: (2019-01-01) -
Superior Stability of Hydroxysafflor Yellow A in Xuebijing Injection and the Associated Mechanism
by: Weiling Pu, et al.
Published: (2017-12-01)