Accelerated cell aging in female APOE-ε4 carriers: implications for hormone therapy use.

Accelerated cell aging in female APOE-ε4 carriers: implications for hormone therapy use.

Apolipoprotein-ε4 (APOE-ε4) is a major genetic risk factor for cognitive decline, Alzheimer's disease (AD) and early mortality. An accelerated rate of biological aging could contribute to this increased risk. Here, we determined whether APOE-ε4 status impacts leukocyte telomere length (TL) and...

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Bibliographic Details
Main Authors: Emily G Jacobs, Candyce Kroenke, Jue Lin, Elissa S Epel, Heather A Kenna, Elizabeth H Blackburn, Natalie L Rasgon
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3572118?pdf=render

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http://europepmc.org/articles/PMC3572118?pdf=render

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