A Retrospective Paired Comparison Between Untargeted Next Generation Sequencing and Conventional Microbiology Tests With Wisely Chosen Metagenomic Sequencing Positive Criteria

A Retrospective Paired Comparison Between Untargeted Next Generation Sequencing and Conventional Microbiology Tests With Wisely Chosen Metagenomic Sequencing Positive Criteria

Objectives: To evaluate the performance of metagenomic next generation sequencing (mNGS) using adequate criteria for the detection of pathogens in lower respiratory tract (LRT) samples with a paired comparison to conventional microbiology tests (CMT).Methods: One hundred sixty-seven patients were re...

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Bibliographic Details
Main Authors: Hanyu Qin, Jinmin Peng, Ling Liu, Jing Wu, Lingai Pan, Xiaobo Huang, Man Huang, Haibo Qiu, Bin Du, The China Critical Care Clinical Trials Group (CCCCTG)
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-10-01
Series:Frontiers in Medicine
Subjects:
metagenomic sequencing
pathogen detection
lower respiratory tract infection
conventional microbiology tests
positive criteria
Online Access:https://www.frontiersin.org/articles/10.3389/fmed.2021.686247/full

Internet

https://www.frontiersin.org/articles/10.3389/fmed.2021.686247/full

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