Diastolic dysfunction of aging is independent of myocardial structure but associated with plasma advanced glycation end-product levels.

Diastolic dysfunction of aging is independent of myocardial structure but associated with plasma advanced glycation end-product levels.

BACKGROUND: Heart failure is associated with abnormalities of myocardial structure, and plasma levels of the advanced glycation end-product (AGE) N(ε)-(carboxymethyl)lysine (CML) correlate with the severity and prognosis of heart failure. Aging is associated with diastolic dysfunction and increased...

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Bibliographic Details
Main Authors: Duncan J Campbell, Jithendra B Somaratne, Alicia J Jenkins, David L Prior, Michael Yii, James F Kenny, Andrew E Newcomb, Casper G Schalkwijk, Mary Jane Black, Darren J Kelly
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3506639?pdf=render

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http://europepmc.org/articles/PMC3506639?pdf=render

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