Comparison of Vascular Perturbations in an Aβ-Injected Animal Model and in AD Brain

The validity of amyloid-β peptide (Aβ1–42) intrahippocampal injection, as an animal model of Alzheimer's disease (AD), has previously been considered in terms of inflammatory reactivity and neuronal damage. In this work, we have extended the testing of the animal model to vasculature by compari...

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Bibliographic Details
Main Authors: Nattinee Jantaratnotai, Jae K. Ryu, Claudia Schwab, Patrick L. McGeer, James G. McLarnon
Format: Article
Language:English
Published: Hindawi Limited 2011-01-01
Series:International Journal of Alzheimer's Disease
Online Access:http://dx.doi.org/10.4061/2011/918280