A detailed modular analysis of heat-shock protein dynamics under acute and chronic stress and its implication in anxiety disorders.

Physiological and psychological stresses cause anxiety disorders such as depression and post-traumatic stress disorder (PTSD) and induce drastic changes at a molecular level in the brain. To counteract this stress, the heat-shock protein (HSP) network plays a vital role in restoring the homeostasis...

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Bibliographic Details
Main Authors: K Sriram, Maria Rodriguez-Fernandez, Francis J Doyle
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3425570?pdf=render