An extended model of vesicle fusion at the plasma membrane to estimate protein lateral diffusion from TIRF microscopy images

An extended model of vesicle fusion at the plasma membrane to estimate protein lateral diffusion from TIRF microscopy images

Abstract Background Characterizing membrane dynamics is a key issue to understand cell exchanges with the extra-cellular medium. Total internal reflection fluorescence microscopy (TIRFM) is well suited to focus on the late steps of exocytosis at the plasma membrane. However, it is still a challengin...

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Bibliographic Details
Main Authors: Antoine Basset, Patrick Bouthemy, Jérôme Boulanger, François Waharte, Jean Salamero, Charles Kervrann
Format: Article
Language:English
Published: BMC 2017-07-01
Series:BMC Bioinformatics
Subjects:
TIRF microscopy
Vesicle fusion model
Molecule diffusion
Protein release rate
Model fitting
Exocytosis
Online Access:http://link.springer.com/article/10.1186/s12859-017-1765-y

Internet

http://link.springer.com/article/10.1186/s12859-017-1765-y

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