Acquiring Metastatic Competence by Oral Squamous Cell Carcinoma Cells Is Associated with Differential Expression of α-Tubulin Isoforms

We performed comparative global proteomics analyses of patient-matched primary (686Tu) and metastatic (686Ln) OSCC cells. The metastatic OSCC 686Ln cells showed greater in vitro migratory/invasive potential and distinct cell shape from their parental primary 686Tu cells. Ettan DIGE analysis revealed...

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Bibliographic Details
Main Authors: Becky Lou, David Engler, William Dubinsky, Jean Wu, Nadarajah Vigneswaran
Format: Article
Language:English
Published: Hindawi Limited 2012-01-01
Series:Journal of Oncology
Online Access:http://dx.doi.org/10.1155/2012/491685