Aberrant upregulation of CaSR promotes pathological new bone formation in ankylosing spondylitis

Aberrant upregulation of CaSR promotes pathological new bone formation in ankylosing spondylitis

Abstract Pathological new bone formation is a typical pathological feature in ankylosing spondylitis (AS), and the underlying molecular mechanism remains elusive. Previous studies have shown that the calcium‐sensing receptor (CaSR) is critical for osteogenic differentiation while also being highly i...

Full description

Bibliographic Details
Main Authors: Xiang Li, Siwen Chen, Zaiying Hu, Dongying Chen, Jianru Wang, Zemin Li, Zihao Li, Haowen Cui, Guo Dai, Lei Liu, Haitao Wang, Kuibo Zhang, Zhaomin Zheng, Zhongping Zhan, Hui Liu
Format: Article
Language:English
Published: Wiley 2020-12-01
Series:EMBO Molecular Medicine
Subjects:
ankylosing spondylitis
CaSR
inflammation
inflammatory cytokines
pathological new bone formation
Online Access:https://doi.org/10.15252/emmm.202012109

Internet

https://doi.org/10.15252/emmm.202012109

Similar Items