In vivo large-scale cortical mapping using channelrhodopsin-2 stimulation in transgenic mice reveals asymmetric and reciprocal relationships between cortical areas

In vivo large-scale cortical mapping using channelrhodopsin-2 stimulation in transgenic mice reveals asymmetric and reciprocal relationships between cortical areas

We have mapped intracortical activity in vivo independent of sensory input using arbitrary point channelrhodopsin-2 (ChR2) stimulation and regional voltage sensitive dye imaging in B6.Cg-Tg (Thy1-COP4/EYFP)18Gfng/J transgenic mice. Photostimulation of subsets of deep layer pyramidal neurons within f...

Full description

Bibliographic Details
Main Authors: Diana H Lim, Majid H Mohajerani, Jeffrey eLeDue, Jamie eBoyd, Shangbin eChen, Timothy H Murphy
Format: Article
Language:English
Published: Frontiers Media S.A. 2012-03-01
Series:Frontiers in Neural Circuits
Subjects:
connectivity
Network analysis
optogenetics
in vivo imaging
channelrhodopsin
cortical mapping
Online Access:http://journal.frontiersin.org/Journal/10.3389/fncir.2012.00011/full

Internet

http://journal.frontiersin.org/Journal/10.3389/fncir.2012.00011/full

Similar Items