Data-Driven Discovery of Immune Contexture Biomarkers

Data-Driven Discovery of Immune Contexture Biomarkers

Background: Features characterizing the immune contexture (IC) in the tumor microenvironment can be prognostic and predictive biomarkers. Identifying novel biomarkers can be challenging due to complex interactions between immune and tumor cells and the abundance of possible features.Methods: We desc...

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Bibliographic Details
Main Authors: Lars Ole Schwen, Emilia Andersson, Konstanty Korski, Nick Weiss, Sabrina Haase, Fabien Gaire, Horst K. Hahn, André Homeyer, Oliver Grimm
Format: Article
Language:English
Published: Frontiers Media S.A. 2018-12-01
Series:Frontiers in Oncology
Subjects:
biomarker discovery
cell-to-cell distances
colorectal cancer
digital biomarkers
immune contexture
spatial heterogeneity
Online Access:https://www.frontiersin.org/article/10.3389/fonc.2018.00627/full

Internet

https://www.frontiersin.org/article/10.3389/fonc.2018.00627/full

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