Surface plasmon resonance unveils important pitfalls of enzyme-linked immunoassay for the detection of anti-infliximab antibodies in patients’ sera

Abstract Measurements of serum concentrations of therapeutic antibodies and anti-drug antibodies (ADA) can support clinical decisions for the management of non-responders, optimizing the therapy. In the present study we compared the results obtained by classical ELISA and a recently proposed surface...

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Bibliographic Details
Main Authors: Marten Beeg, Cesare Burti, Eleonora Allocati, Clorinda Ciafardini, Rita Banzi, Alessandro Nobili, Flavio Caprioli, Silvio Garattini, Marco Gobbi
Format: Article
Language:English
Published: Nature Publishing Group 2021-07-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-021-94431-x