HIV Nef-mediated Ubiquitination of BCL2: Implications in Autophagy and Apoptosis

Ubiquitination is a process that acts upon every step of the HIV replication cycle. The activity, subcellular localization, and stability of HIV dependency factors as well as negative modulators can be affected by ubiquitination. These modifications consequently have an impact on the progression and...

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Bibliographic Details
Main Authors: Sergio Castro-Gonzalez, Sydney Simpson, Yuhang Shi, Yuexuan Chen, Jared Benjamin, Ruth Serra-Moreno
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-05-01
Series:Frontiers in Immunology
Subjects:
HIV
Nef
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2021.682624/full