Oligodendrocytes in the Mouse Corpus Callosum Maintain Axonal Function by Delivery of Glucose

Summary: In the optic nerve, oligodendrocytes maintain axonal function by supplying lactate as an energy substrate. Here, we report that, in acute brain slices of the mouse corpus callosum, exogenous glucose deprivation (EGD) abolished compound action potentials (CAPs), which neither lactate nor pyr...

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Bibliographic Details
Main Authors: Niklas Meyer, Nadine Richter, Zoya Fan, Gabrielle Siemonsmeier, Tatyana Pivneva, Philipp Jordan, Christian Steinhäuser, Marcus Semtner, Christiane Nolte, Helmut Kettenmann
Format: Article
Language:English
Published: Elsevier 2018-02-01
Series:Cell Reports
Online Access:http://www.sciencedirect.com/science/article/pii/S2211124718301906