TAP1-deficiency does not alter atherosclerosis development in Apoe-/- mice.

TAP1-deficiency does not alter atherosclerosis development in Apoe-/- mice.

Antigen presenting cells (APC) have the ability to present both extra-cellular and intra-cellular antigens via MHC class I molecules to CD8(+) T cells. The cross presentation of extra-cellular antigens is reduced in mice with deficient Antigen Peptide Transporter 1 (TAP1)-dependent MHC class I antig...

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Bibliographic Details
Main Authors: Daniel Kolbus, Irena Ljungcrantz, Ingrid Söderberg, Ragnar Alm, Harry Björkbacka, Jan Nilsson, Gunilla Nordin Fredrikson
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3316507?pdf=render

Internet

http://europepmc.org/articles/PMC3316507?pdf=render

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