LDH Isotyping for Checkpoint Inhibitor Response Prediction in Patients with Metastatic Melanoma
Serum lactate dehydrogenase (LDH) levels are inversely related with response to immune checkpoint inhibitors (ICIs) in patients with metastatic melanoma. LDH is a key regulator of glycolysis, a pathway known to be upregulated in malignant tumors and to negatively affect antitumor immunity. We hypoth...
| Main Authors: | , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
MDPI AG
2021-04-01
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| Series: | Immuno |
| Subjects: | |
| Online Access: | https://www.mdpi.com/2673-5601/1/2/5 |