Detection of cancer clones in human colorectal adenoma as revealed by increased DNA instability and other bio-markers

An immunohistochemical differential staining of cancerous cells with anti-cytidine antibody after denaturation of nuclear DNA by acid hydrolysis with 2N HCl at 30°C for 20 min (DNA-instability test) has been used as a marker for malignancy. The test was applied to bioptic tissues of human colorectal...

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Bibliographic Details
Main Authors: Y Jin, A Sun, S Noriki, Y Imamura, M Fukuda
Format: Article
Language:English
Published: PAGEPress Publications 2009-06-01
Series:European Journal of Histochemistry
Online Access:http://www.ejh.it/index.php/ejh/article/view/1005