Proteome Profiling Uncovers an Autoimmune Response Signature That Reflects Ovarian Cancer Pathogenesis

Proteome Profiling Uncovers an Autoimmune Response Signature That Reflects Ovarian Cancer Pathogenesis

Harnessing the immune response to tumor antigens in the form of autoantibodies, which occurs early during tumor development, has relevance to the detection of cancer at early stages. We conducted an initial screen of antigens associated with an autoantibody response in serous ovarian cancer using re...

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Bibliographic Details
Main Authors: Makoto Kobayashi, Hiroyuki Katayama, Ehsan Irajizad, Jody V. Vykoukal, Johannes F. Fahrmann, Deepali L. Kundnani, Chuan-Yih Yu, Yining Cai, Fu Chung Hsiao, Wei-Lei Yang, Zhen Lu, Joseph Celestino, James P. Long, Kim-Ann Do, Karen H. Lu, Jon J. Ladd, Nicole Urban, Robert C. Bast Jr., Samir M. Hanash
Format: Article
Language:English
Published: MDPI AG 2020-02-01
Series:Cancers
Subjects:
ovarian cancer
autoantibody signature
tp53–myc network
antigen–antibody complexes
Online Access:https://www.mdpi.com/2072-6694/12/2/485

Internet

https://www.mdpi.com/2072-6694/12/2/485

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