Construction of an Alternative NAD+ De Novo Biosynthesis Pathway

Construction of an Alternative NAD+ De Novo Biosynthesis Pathway

Abstract Nicotinamide adenine dinucleotide (NAD+) is a life essential molecule involved in versatile biological processes. To date, only two de novo biosynthetic routes to NAD+ are described, both of which start from a proteinogenic amino acid and are tightly controlled. Here, a de novo quinolinic a...

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Bibliographic Details
Main Authors: Yong Ding, Xinli Li, Geoff P. Horsman, Pengwei Li, Min Wang, Jine Li, Zhilong Zhang, Weifeng Liu, Bian Wu, Yong Tao, Yihua Chen
Format: Article
Language:English
Published: Wiley 2021-05-01
Series:Advanced Science
Subjects:
cell factories
chiral amines
cofactor engineering
DHHA dehydrogenases
NAD+ biosynthesis
Online Access:https://doi.org/10.1002/advs.202004632

Internet

https://doi.org/10.1002/advs.202004632

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