Three dimensional structure directs T-cell epitope dominance associated with allergy
<p>Abstract</p> <p>Background</p> <p>CD4+ T-cell epitope immunodominance is not adequately explained by peptide selectivity in class II major histocompatibility proteins, but it has been correlated with adjacent segments of conformational flexibility in several antigens...
Main Authors: | , |
---|---|
Format: | Article |
Language: | English |
Published: |
BMC
2008-09-01
|
Series: | Clinical and Molecular Allergy |
Online Access: | http://www.clinicalmolecularallergy.com/content/6/1/9 |