Three dimensional structure directs T-cell epitope dominance associated with allergy

<p>Abstract</p> <p>Background</p> <p>CD4+ T-cell epitope immunodominance is not adequately explained by peptide selectivity in class II major histocompatibility proteins, but it has been correlated with adjacent segments of conformational flexibility in several antigens...

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Bibliographic Details
Main Authors: Landry Samuel J, Melton Scott J
Format: Article
Language:English
Published: BMC 2008-09-01
Series:Clinical and Molecular Allergy
Online Access:http://www.clinicalmolecularallergy.com/content/6/1/9