Therapeutic efficacy of intra-arterial administration of induced pluripotent stem cells-derived neural progenitor cells in acute experimental ischemic stroke in rats

Therapeutic efficacy of intra-arterial administration of induced pluripotent stem cells-derived neural progenitor cells in acute experimental ischemic stroke in rats

Aim. Neural progenitor cells (NPC) are used for the development of cell therapies of neurological diseases. Their stereotaxic transplantation in the middle cerebral artery occlusion (MCAO) model imitating ischemic stroke results in symptom aleviation. However, exploration of less invasive transplant...

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Bibliographic Details
Main Authors: D. D. Namestnikova, I. L. Gubskiy, D. I. Salikhova, G. E. Leonov, K. K. Sukhinich, P. A. Melnikov, D. A. Vishnevskiy, E. A. Cherkashova, A. N. Gabashvili, T. B. Bukharova, V. V. Burunova, T. Kh. Fatkhudinov, V. P. Chekhonin, L. V. Gubsky, S. L. Kiselev, D. V. Goldstein, K. N. Yarygin
Format: Article
Language:Russian
Published: Federal Research Center of Transplantology and Artificial Organs named after V.I.Shumakov 2019-05-01
Series:Vestnik Transplantologii i Iskusstvennyh Organov
Subjects:
neural progenitor cells
induced pluripotent stem cells
cell therapy
ischemic stroke
middle cerebral artery occlusion model
Online Access:https://journal.transpl.ru/vtio/article/view/1001

Internet

https://journal.transpl.ru/vtio/article/view/1001

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