Acute inhibition of hepatic β-oxidation in APOE*3Leiden mice does not affect hepatic VLDL secretion or insulin sensitivity

Acute inhibition of hepatic β-oxidation in APOE*3Leiden mice does not affect hepatic VLDL secretion or insulin sensitivity

Hepatic VLDL and glucose production is enhanced in type 2 diabetes and associated with hepatic steatosis. Whether the derangements in hepatic metabolism are attributable to steatosis or to the increased availability of FA metabolites is not known. We used methyl palmoxirate (MP), an inhibitor of car...

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Bibliographic Details
Main Authors: Ilse Duivenvoorden, Bas Teusink, Patrick C.N. Rensen, Folkert Kuipers, Johannes A. Romijn, Louis M. Havekes, Peter J. Voshol
Format: Article
Language:English
Published: Elsevier 2005-05-01
Series:Journal of Lipid Research
Subjects:
triglycerides
fatty acids
steatosis
glucose metabolism
very low density lipoprotein
Online Access:http://www.sciencedirect.com/science/article/pii/S002222752033981X

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http://www.sciencedirect.com/science/article/pii/S002222752033981X

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