Acute inhibition of hepatic β-oxidation in APOE*3Leiden mice does not affect hepatic VLDL secretion or insulin sensitivity
Hepatic VLDL and glucose production is enhanced in type 2 diabetes and associated with hepatic steatosis. Whether the derangements in hepatic metabolism are attributable to steatosis or to the increased availability of FA metabolites is not known. We used methyl palmoxirate (MP), an inhibitor of car...
Main Authors: | Ilse Duivenvoorden, Bas Teusink, Patrick C.N. Rensen, Folkert Kuipers, Johannes A. Romijn, Louis M. Havekes, Peter J. Voshol |
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Format: | Article |
Language: | English |
Published: |
Elsevier
2005-05-01
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Series: | Journal of Lipid Research |
Subjects: | |
Online Access: | http://www.sciencedirect.com/science/article/pii/S002222752033981X |
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