Domain Structures and Inter-Domain Interactions Defining the Holoenzyme Architecture of Archaeal D-Family DNA Polymerase

Domain Structures and Inter-Domain Interactions Defining the Holoenzyme Architecture of Archaeal D-Family DNA Polymerase

Archaea-specific D-family DNA polymerase (PolD) forms a dimeric heterodimer consisting of two large polymerase subunits and two small exonuclease subunits. According to the protein-protein interactions identified among the domains of large and small subunits of PolD, a symmetrical model for the doma...

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Bibliographic Details
Main Authors: Hideshi Yokoyama, Kazuhiko Yamasaki, Ikuo Matsui, Eriko Matsui
Format: Article
Language:English
Published: MDPI AG 2013-07-01
Series:Life
Subjects:
D-family DNA polymerase
DNA replication
binding domain
molecular structure
hyperthermophilic archaea
Pyrococcus
Online Access:http://www.mdpi.com/2075-1729/3/3/375

Internet

http://www.mdpi.com/2075-1729/3/3/375

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