Secondary Malignancy Risk Following Proton vs. X-ray Treatment of Mediastinal Malignant Lymphoma: A Comparative Modeling Study of Thoracic Organ-Specific Cancer Risk

Secondary Malignancy Risk Following Proton vs. X-ray Treatment of Mediastinal Malignant Lymphoma: A Comparative Modeling Study of Thoracic Organ-Specific Cancer Risk

Purpose: Proton radiotherapy (PRT) is potentially associated with a lower risk for secondary malignancies due to a decreased integral dose to the surrounding organs at risk (OARs). Prospective trials confirming this are lacking due to the need for long-term follow-up and the ethical complexities of...

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Bibliographic Details
Main Authors: Laila König, Peter Haering, Clemens Lang, Mona Splinter, Bastian von Nettelbladt, Fabian Weykamp, Philipp Hoegen, Jonathan W. Lischalk, Klaus Herfarth, Jürgen Debus, Juliane Hörner-Rieber
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-07-01
Series:Frontiers in Oncology
Subjects:
mediastinal lymphoma
proton radiotherapy
intensity modulated radiotherapy
photon radiotherapy
secondary malignancies
risk
Online Access:https://www.frontiersin.org/article/10.3389/fonc.2020.00989/full

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https://www.frontiersin.org/article/10.3389/fonc.2020.00989/full

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