Tumor-draining lymph node is important for a robust abscopal effect stimulated by radiotherapy

Background Radiotherapy (RT) has been shown to stimulate an antitumor immune response in irradiated tumors as well as unirradiated distant sites (abscopal effect). Previous studies have demonstrated a role for the tumor-draining lymph node (LN) in mediating an anti-programmed death-1 (PD-1)/programm...

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Bibliographic Details
Main Authors: Zachary S Buchwald, Tahseen H Nasti, Judong Lee, Christiane S Eberhardt, Andres Wieland, Se Jin Im, Mohammad K Khan
Format: Article
Language:English
Published: BMJ Publishing Group 2020-07-01
Series:Journal for ImmunoTherapy of Cancer
Online Access:https://jitc.bmj.com/content/8/2/e000867.full