Anillin facilitates septin assembly to prevent pathological outfoldings of central nervous system myelin

Anillin facilitates septin assembly to prevent pathological outfoldings of central nervous system myelin

Myelin serves as an axonal insulator that facilitates rapid nerve conduction along axons. By transmission electron microscopy, a healthy myelin sheath comprises compacted membrane layers spiraling around the cross-sectioned axon. Previously we identified the assembly of septin filaments in the inner...

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Bibliographic Details
Main Authors: Michelle S Erwig, Julia Patzig, Anna M Steyer, Payam Dibaj, Mareike Heilmann, Ingo Heilmann, Ramona B Jung, Kathrin Kusch, Wiebke Möbius, Olaf Jahn, Klaus-Armin Nave, Hauke B Werner
Format: Article
Language:English
Published: eLife Sciences Publications Ltd 2019-01-01
Series:eLife
Subjects:
oligodendrocyte
myelin pathology
myelin outfoldings / redundant myelin
focused ion beam scanning electron microscopy (FIB-SEM)
septin filament
anillin (ANLN)
Online Access:https://elifesciences.org/articles/43888

Internet

https://elifesciences.org/articles/43888

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