Albumin-Modified Melanin-Silica Hybrid Nanoparticles Target Breast Cancer Cells via a SPARC-Dependent Mechanism

Albumin-Modified Melanin-Silica Hybrid Nanoparticles Target Breast Cancer Cells via a SPARC-Dependent Mechanism

Bioconjugation of a recently developed photoacoustic nanoprobe, based on silica-templated eumelanin-silver hybrid nanoparticles (MelaSil_Ag-NPs), with human serum albumin (HSA) is disclosed herein as an efficient and practical strategy to improve photostability and to perform SPARC mediated internal...

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Bibliographic Details
Main Authors: Gennaro Sanità, Paolo Armanetti, Brigida Silvestri, Barbara Carrese, Gaetano Calì, Giulio Pota, Alessandro Pezzella, Marco d’Ischia, Giuseppina Luciani, Luca Menichetti, Annalisa Lamberti
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-07-01
Series:Frontiers in Bioengineering and Biotechnology
Subjects:
albumin
SPARC
nanoparticles
photoacoustic
melanin
Online Access:https://www.frontiersin.org/article/10.3389/fbioe.2020.00765/full

Internet

https://www.frontiersin.org/article/10.3389/fbioe.2020.00765/full

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