Parental LTRs are important in a construct of a stable and efficient replication-competent infectious molecular clone of HIV-1 CRF08_BC.

Circulating recombinant forms (CRFs) of HIV-1 have been identified in southern China in recent years. CRF08_BC is one of the most predominant subtypes circulating in China. In order to study HIV subtype biology and to provide a tool for biotechnological applications, the first full-length replicatio...

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Bibliographic Details
Main Authors: Qiwei Zhang, Xiaomin Zhang, Hao Wu, Donald Seto, Hao-Jie Zhang, Zhiwei Chen, Chengsong Wan, Bo-Jian Zheng
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/22363589/?tool=EBI