Frustrated endocytosis controls contractility-independent mechanotransduction at clathrin-coated structures

Frustrated endocytosis controls contractility-independent mechanotransduction at clathrin-coated structures

Cells sense mechanical properties of their environment using various cellular structures including focal adhesions. Here, the authors identify flat clathrin-coated structures (CCSs) as mechanosensitive signaling platforms that form independently of contractility and in response to substrate rigidity...

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Bibliographic Details
Main Authors: Francesco Baschieri, Stéphane Dayot, Nadia Elkhatib, Nathalie Ly, Anahi Capmany, Kristine Schauer, Timo Betz, Danijela Matic Vignjevic, Renaud Poincloux, Guillaume Montagnac
Format: Article
Language:English
Published: Nature Publishing Group 2018-09-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-018-06367-y

Internet

https://doi.org/10.1038/s41467-018-06367-y

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