ScalaFlux: A scalable approach to quantify fluxes in metabolic subnetworks.

13C-metabolic flux analysis (13C-MFA) allows metabolic fluxes to be quantified in living organisms and is a major tool in biotechnology and systems biology. Current 13C-MFA approaches model label propagation starting from the extracellular 13C-labeled nutrient(s), which limits their applicability to...

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Bibliographic Details
Main Authors: Pierre Millard, Uwe Schmitt, Patrick Kiefer, Julia A Vorholt, Stéphanie Heux, Jean-Charles Portais
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2020-04-01
Series:PLoS Computational Biology
Online Access:https://doi.org/10.1371/journal.pcbi.1007799