Concurrent T790M and L858R mutations in treatment-naïve metastatic non-small-cell lung cancer: A therapeutic challenge – Current treatment strategies and promising therapies of the future in a nutshell

De novo (pretreatment) epidermal growth factor receptor T790M mutation in non-small-cell lung cancer (NSCLC) is rare when detected by standard genotyping methods. We present a case of concurrent de novo T790M and L858R mutations detected by direct sequencing in treatment-naïve metastatic NSCLC. This...

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Bibliographic Details
Main Authors: M. C. Suresh Babu, K. Govind Babu, K. N. Lokesh, L. K. Rajeev, Gita R. Bhat
Format: Article
Language:English
Published: Thieme Medical Publishers, Inc. 2017-01-01
Series:Asian Journal of Oncology
Subjects:
Online Access:http://www.thieme-connect.de/DOI/DOI?10.4103/2454-6798.209336