N332-Directed broadly neutralizing antibodies use diverse modes of HIV-1 recognition: inferences from heavy-light chain complementation of function.

N332-Directed broadly neutralizing antibodies use diverse modes of HIV-1 recognition: inferences from heavy-light chain complementation of function.

Dozens of broadly neutralizing HIV-1 antibodies have been isolated in the last few years from the sera of HIV-1-infected individuals. Only a limited number of regions on the HIV-1 spike, however, are recognized by these antibodies. One of these regions (N332) is characterized by an N-linked glycan a...

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Bibliographic Details
Main Authors: Marie Pancera, Yongping Yang, Mark K Louder, Jason Gorman, Gabriel Lu, Jason S McLellan, Jonathan Stuckey, Jiang Zhu, Dennis R Burton, Wayne C Koff, John R Mascola, Peter D Kwong
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3576407?pdf=render

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http://europepmc.org/articles/PMC3576407?pdf=render

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