QSAR Study and Molecular Design of Open-Chain Enaminones as Anticonvulsant Agents

QSAR Study and Molecular Design of Open-Chain Enaminones as Anticonvulsant Agents

Present work employs the QSAR formalism to predict the ED50 anticonvulsant activity of ringed-enaminones, in order to apply these relationships for the prediction of unknown open-chain compounds containing the same types of functional groups in their molecular structure. Two different modeling appro...

Full description

Bibliographic Details
Main Authors: Juan C. Garro Martinez, Pablo R. Duchowicz, Mario R. Estrada, Graciela N. Zamarbide, Eduardo A. Castro
Format: Article
Language:English
Published: MDPI AG 2011-12-01
Series:International Journal of Molecular Sciences
Subjects:
QSAR theory
anticonvulsant activity
open-chain enaminone
flexible descriptors
Online Access:http://www.mdpi.com/1422-0067/12/12/9354/

Internet

http://www.mdpi.com/1422-0067/12/12/9354/

Similar Items