BASiCS: Bayesian Analysis of Single-Cell Sequencing Data.

Single-cell mRNA sequencing can uncover novel cell-to-cell heterogeneity in gene expression levels in seemingly homogeneous populations of cells. However, these experiments are prone to high levels of unexplained technical noise, creating new challenges for identifying genes that show genuine hetero...

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Bibliographic Details
Main Authors: Catalina A Vallejos, John C Marioni, Sylvia Richardson
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2015-06-01
Series:PLoS Computational Biology
Online Access:https://doi.org/10.1371/journal.pcbi.1004333