Immunological activity difference between native calreticulin monomers and oligomers.

We have recently demonstrated that the greatly increased immunological activities of recombinant murine calreticulin (rCRT) are largely attributed to its self-oligomerization. Although native CRT (nCRT) can also oligomerize under stress conditions in vitro, whether this phenomenon could occur inside...

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Bibliographic Details
Main Authors: Mi-chun He, Jun Wang, Jian Wu, Fang-yuan Gong, Chao Hong, Yun Xia, Li-juan Zhang, Wan-rong Bao, Xiao-Ming Gao
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4149419?pdf=render