Detecting selection in low-coverage high-throughput sequencing data using principal component analysis

Abstract Background Identification of selection signatures between populations is often an important part of a population genetic study. Leveraging high-throughput DNA sequencing larger sample sizes of populations with similar ancestries has become increasingly common. This has led to the need of me...

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Bibliographic Details
Main Authors: Jonas Meisner, Anders Albrechtsen, Kristian Hanghøj
Format: Article
Language:English
Published: BMC 2021-09-01
Series:BMC Bioinformatics
Online Access:https://doi.org/10.1186/s12859-021-04375-2