Adipose-Derived Stem Cells from Obese Donors Polarize Macrophages and Microglia toward a Pro-Inflammatory Phenotype

Adipose-Derived Stem Cells from Obese Donors Polarize Macrophages and Microglia toward a Pro-Inflammatory Phenotype

Macrophages and microglia represent the primary phagocytes and first line of defense in the peripheral and central immune systems. They activate and polarize into a spectrum of pro- and anti-inflammatory phenotypes in response to various stimuli. This activation is tightly regulated to balance the a...

Full description

Bibliographic Details
Main Authors: Mark A. A. Harrison, Rachel M. Wise, Brooke P. Benjamin, Emily M. Hochreiner, Omair A. Mohiuddin, Bruce A. Bunnell
Format: Article
Language:English
Published: MDPI AG 2021-12-01
Series:Cells
Subjects:
adipose tissue
adipose stem cells (ASCs)
obesity
polarization
macrophage
microglia
Online Access:https://www.mdpi.com/2073-4409/10/1/26

Internet

https://www.mdpi.com/2073-4409/10/1/26

Similar Items